BIONEXTS EDUCATION

  Stem cells are a unique type of cell in the human body with the remarkable ability to develop into various specialized cell types.  They are characterized by   Totipotent:  Totipotent stem cells are the most versatile and potent type of stem cells. These cells have the ability to give rise to all cell types of the organism, including the embryonic and extraembryonic tissues. In other words, totipotent cells have the potential to differentiate into any cell type of the body as well as the tissues that support embryonic development, such as the placenta. The zygote, which is formed by the fusion of a sperm and an egg, is considered totipotent as it has the capacity to develop into a complete organism. Pluripotent : Pluripotent stem cells are slightly more specialized than totipotent stem cells but still possess a remarkable ability to differentiate into a wide range of cell types. Pluripotent cells have the potential to give rise to cells derived from all three germ ...

  Introduction CRISPR-Cas9  is a revolutionary gene editing technology that has transformed the field of molecular biology and genetics. This lecture will explore the principles, mechanisms, applications, and ethical considerations of CRISPR-Cas9 gene editing. Learning Objectives By the end of this lecture, you should be able to: Understand the fundamental principles of CRISPR-Cas9 gene editing. Describe the mechanisms of CRISPR-Cas9 technology. Recognize the applications and implications of CRISPR-Cas9 in various fields. Principles of CRISPR-Cas9 Gene Editing 1. CRISPR-Cas System: CRISPR  stands for Clustered Regularly Interspaced Short Palindromic Repeats. It's a natural defence mechanism in bacteria and archaea against invading viruses. Cas9  is an enzyme that acts like molecular scissors, cutting DNA at specific locations. 2. Targeted Gene Editing: CRISPR-Cas9  allows precise modification of genes by guiding Cas9 to a specific DNA  sequence using a guid...